Organ on a chip: the Next Generation Teaching Platform for Biomedical Engineering
Recent developed Organ-on-a-chip (OOC) is an innovative approach to studying human organs and tissues by replicating their key features and functions on a miniature scale contributing the healthcare. Providing the learning environment, knowledge’s and technologies on OOC helps students understand the developmental biology, cellular interaction, and disease pathological development, improving the learning outcomes for students with a biomedical related major. It also provides a platform for students to test their medical device designs without using animal models. Despite the advancement of OCC and their promising potentials in enhancing students’ learning experience, CUHK(SZ) lacks of the facilities and platform for OOC which are critical for students with a biomedical related major or other students who are interested in OOC.
Therefore, this proposal aims to build a teaching platform on OOC fabrication, providing a library of OOC including cardiac organ chip, brain organ chip, breast cancer organ chip, and liver organ chip that could be utilized in the relevant courses. In addition to facilitate existing teaching, OOC platform will also regularly organize seminar and workshop sessions, covering the fundamentals of microfluidics, cell culture techniques, and the use of biomaterials to create realistic organ environments, equip students with skill in OOC fabrication and downstream applications. Students will gain insights into the applications of organ-on-a-chip systems for drug development, personalized medicine, and disease modeling. Furthermore, they will learn about the ethical implications and challenges associated with this technology, fostering critical thinking and responsible innovation, consequently enhancing the teaching outcome in general.